Associations of elevated interleukin-6 and C-reactive protein levels with mortality in the elderly
TB Harris, L Ferrucci, RP Tracy, MC Corti… - The American journal of …, 1999 - Elsevier
PURPOSE: To investigate whether interleukin-6 and C-reactive protein levels predict all-
cause and cause-specific mortality in a population-based sample of nondisabled older
people. SUBJECTS AND METHODS: A sample of 1,293 healthy, nondisabled participants in
the Iowa 65+ Rural Health Study was followed prospectively for a mean of 4.6 years. Plasma
interleukin-6 and C-reactive protein levels were measured in specimens obtained from 1987
to 1989. RESULTS: Higher interleukin-6 levels were associated with a twofold greater risk of …
cause and cause-specific mortality in a population-based sample of nondisabled older
people. SUBJECTS AND METHODS: A sample of 1,293 healthy, nondisabled participants in
the Iowa 65+ Rural Health Study was followed prospectively for a mean of 4.6 years. Plasma
interleukin-6 and C-reactive protein levels were measured in specimens obtained from 1987
to 1989. RESULTS: Higher interleukin-6 levels were associated with a twofold greater risk of …