[HTML][HTML] High-resolution array comparative genomic hybridization analysis of human bronchial and salivary adenoid cystic carcinoma
A Bernheim, S Toujani, P Saulnier, T Robert… - Laboratory …, 2008 - Elsevier
Adenoid cystic carcinoma (ACC) is a rare but distinctive tumor. Oligonucleotide array
comparative genomic hybridization has been applied for cataloging genomic copy number
alterations (CNAs) in 17 frozen salivary or bronchial tumors. Only four whole chromosome
CNAs were found, and most cases had 2–4 segmental CNAs. No high level amplification
was observed. There were recurrent gains at 7p15. 2, 17q21–25, and 22q11–13, and
recurrent losses at 1p35, 6q22–25, 8q12–13, 9p21, 12q12–13, and 17p11–13. The minimal …
comparative genomic hybridization has been applied for cataloging genomic copy number
alterations (CNAs) in 17 frozen salivary or bronchial tumors. Only four whole chromosome
CNAs were found, and most cases had 2–4 segmental CNAs. No high level amplification
was observed. There were recurrent gains at 7p15. 2, 17q21–25, and 22q11–13, and
recurrent losses at 1p35, 6q22–25, 8q12–13, 9p21, 12q12–13, and 17p11–13. The minimal …
