[HTML][HTML] Effects of novel capsinoid treatment on fatness and energy metabolism in humans: possible pharmacogenetic implications

S Snitker, Y Fujishima, H Shen, S Ott… - The American journal of …, 2009 - Elsevier
Abstract Background Capsinoids from the Capsicum genus of plants are nonpungent
capsaicin-related substances with effects on metabolism and body weight in animals.
Objectives Our objectives were to explore the safety and efficacy of capsinoids taken orally
(6 mg/d) for weight loss, fat loss, and change in metabolism and to examine whether
candidate genes are predictors of capsinoid response. Design This was a 12-wk, placebo-
controlled, double-blind, randomized study. Eligibility criteria included a body mass index …