Heat shock-like protein is transferred from glia to axon
M Tytell, SG Greenberg, RJ Lasek - Brain research, 1986 - Elsevier
M Tytell, SG Greenberg, RJ Lasek
Brain research, 1986•ElsevierGlia-axon protein transfer was examined in the squid giant axon. Proteins synthesized by
the glial sheath surrounding the axon were labeled with [3 H] leucine. Raising the
temperature of the incubation medium from 20° C to 30° C increased the synthesis of glial
proteins that resembled heat-shock proteins. These proteins were among the group known
to be transferred into the axon 12, 18. Thus, glia provide the axon with proteins that may be
involved in the reaction totrauma.
the glial sheath surrounding the axon were labeled with [3 H] leucine. Raising the
temperature of the incubation medium from 20° C to 30° C increased the synthesis of glial
proteins that resembled heat-shock proteins. These proteins were among the group known
to be transferred into the axon 12, 18. Thus, glia provide the axon with proteins that may be
involved in the reaction totrauma.
Abstract
Glia-axon protein transfer was examined in the squid giant axon. Proteins synthesized by the glial sheath surrounding the axon were labeled with [3H]leucine. Raising the temperature of the incubation medium from 20 °C to 30 °C increased the synthesis of glial proteins that resembled heat-shock proteins. These proteins were among the group known to be transferred into the axon12,18. Thus, glia provide the axon with proteins that may be involved in the reaction totrauma.
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