[32] Thimet oligopeptidase and oligopeptidase M or neurolysin

AJ Barrett, MA Brown, PM Dando, CG Knight… - Methods in …, 1995 - Elsevier
Thimet oligopeptidase (TOP) has been" discovered" independently on a number of different
occasions, and only recently have the several separate identities of the enzyme been
unified. Pz-peptidase was a eukaryotic enzyme that hydrolyzed the Pz-peptide, 4-
phenylazobenzyloxycarbonyl-Pro-Leu~-Gly-Pro-D-Arg, 1 which had been designed as a
synthetic substrate for bacterial collagenase, t Much of the work on Pz-peptidase was
stimulated by the idea that the enzyme might participate in the physiological turnover of …