[HTML][HTML] Intraflagellar transport and cilium-based signaling

JM Scholey, KV Anderson - Cell, 2006 - cell.com
JM Scholey, KV Anderson
Cell, 2006cell.com
Cilia are specialized structures that not only play diverse roles in cell motility but also
transmit signals to the cytoplasm and nucleus to control gene expression, cell function,
animal development, and behavior. Cilia are assembled and maintained by the intraflagellar
transport (IFT) machinery, which coordinates rapid, bidirectional transport between the cell
body and the distal tip of the cilium. A new study (Wang et al., 2006) illuminates the role of
IFT in cilium-based signaling during mating in the alga Chlamydomonas.
Cilia are specialized structures that not only play diverse roles in cell motility but also transmit signals to the cytoplasm and nucleus to control gene expression, cell function, animal development, and behavior. Cilia are assembled and maintained by the intraflagellar transport (IFT) machinery, which coordinates rapid, bidirectional transport between the cell body and the distal tip of the cilium. A new study (Wang et al., 2006) illuminates the role of IFT in cilium-based signaling during mating in the alga Chlamydomonas.
cell.com