Aldehyde dehydrogenase as an alternative to enumeration of total and viable CD34+ cells in autologous hematopoietic progenitor cell transplantation

M Veeraputhiran, L Katragadda, A Balamurugan… - Cytotherapy, 2011 - Elsevier
We validated the correlation of aldehyde dehydrogenase ALDH br cells with total and viable
CD34+ cells in fresh and thawed hematopoietic progenitor cell (HPC) products, and looked
for a correlation with time to white blood cell (WBC) and platelet engraftment after
autologous transplantation, using simple linear regression analyzes. We found a significant
correlation between pre-freeze ALDH br cell numbers and pre-freeze total CD34+(P<
0.001), viable CD34+(P< 0.001) and post-thaw viable CD34+(P< 0.001) cell numbers. We …