CD10: a valuable tool for the light microscopic diagnosis of microvillous inclusion disease (familial microvillous atrophy)
GM Groisman, M Amar, E Livne - The American journal of surgical …, 2002 - journals.lww.com
Microvillous inclusion disease (MID) is a specific disorder of the intestinal brush border that
leads to intractable secretory diarrhea in infants. At present, electron microscopic analysis is
required for its definitive diagnosis. However, this technique is not always available or
feasible, and the diagnostic microvillous inclusions may not be evident in all specimens.
Accordingly, the availability of a panel of histochemical and immunohistochemical stains
displaying a specific staining pattern for MID will allow pathologists to reach a definitive …
leads to intractable secretory diarrhea in infants. At present, electron microscopic analysis is
required for its definitive diagnosis. However, this technique is not always available or
feasible, and the diagnostic microvillous inclusions may not be evident in all specimens.
Accordingly, the availability of a panel of histochemical and immunohistochemical stains
displaying a specific staining pattern for MID will allow pathologists to reach a definitive …