Importance Barrett esophagus, a complication of gastroesophageal reflux disease (GERD),
predisposes patients to esophageal adenocarcinoma, a tumor that has increased in
incidence more than 7-fold over the past several decades. Controversy exists regarding the
issues of endoscopic screening and surveillance for Barrett esophagus, treatment for the
underlying GERD, and the role of endoscopic eradication therapy. Objectives To review
current concepts on the pathogenesis, diagnosis, and treatment of Barrett esophagus; to …