Mechanical injury increases bFGF and CNTF mRNA expression in the mouse retina
WEI Cao, R Wen, F Li, MM Lavail… - Experimental eye …, 1997 - Elsevier
We characterized the survival-factor response of the normal mouse retina to mechanical
injury by examining the expression of mRNAs for basic fibroblast growth factor (bFGF),
ciliary neurotrophic factor (CNTF), and their receptors, FGF receptor-1 (FGFR-1) and CNTF
receptor alpha (CNTFR-alpha). The retina was injured by making an incision through the
choroid and retinal pigment epithelium that penetrated the subretinal space of each eye of
an adult BALB/c mouse. Retinas were taken 6 hr, 12 hr, 1, 2, 4, 7, 10 and 16 days post …
injury by examining the expression of mRNAs for basic fibroblast growth factor (bFGF),
ciliary neurotrophic factor (CNTF), and their receptors, FGF receptor-1 (FGFR-1) and CNTF
receptor alpha (CNTFR-alpha). The retina was injured by making an incision through the
choroid and retinal pigment epithelium that penetrated the subretinal space of each eye of
an adult BALB/c mouse. Retinas were taken 6 hr, 12 hr, 1, 2, 4, 7, 10 and 16 days post …