Angiogenesis in pulmonary fibrosis: too much or not enough?

C Hanumegowda, L Farkas, M Kolb - Chest, 2012 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually fatal disease,
based on a multifaceted and incompletely understood pathogenesis. Some of the cellular
and molecular mechanisms of vascular remodeling have been experimentally explored, and
it is obvious that alterations of microvessels are involved in IPF. These can, among others,
lead to the development of pulmonary hypertension. In order to understand the process of
vascular integrity and repair, it is necessary to identify the factors associated with …