Independent association of urinary F2-isoprostanes with survival in pulmonary arterial hypertension

JL Cracowski, B Degano, F Chabot, J Labarère… - Chest, 2012 - Elsevier
Objectives Within the past decade, biochemical markers have emerged as attractive tools to
assess pulmonary arterial hypertension (PAH) prognosis, being noninvasive and easily
repeatable. The objective of this study was to determine whether biomarkers measured at
initial diagnostic right-sided heart catheterization predict 3-year all-cause mortality for
incident cases of PAH independently of clinical and hemodynamic parameters. Methods
Patients with incident PAH were enrolled between December 2003 and April 2006 in six …