[HTML][HTML] Programmed death ligand-1 expression in non-small cell lung cancer
V Velcheti, KA Schalper, DE Carvajal… - Laboratory …, 2014 - Elsevier
Recent strategies targeting the interaction of the programmed cell death ligand-1 (PD-L1, B7-
H1, CD274) with its receptor, PD-1, resulted in promising activity in early phase clinical trials.
In this study, we used various antibodies and in situ mRNA hybridization to measure PD-L1
in non-small cell lung cancer (NSCLC) using a quantitative fluorescence (QIF) approach to
determine the frequency of expression and prognostic value in two independent
populations. A control tissue microarray (TMA) was constructed using PD-L1-transfected …
H1, CD274) with its receptor, PD-1, resulted in promising activity in early phase clinical trials.
In this study, we used various antibodies and in situ mRNA hybridization to measure PD-L1
in non-small cell lung cancer (NSCLC) using a quantitative fluorescence (QIF) approach to
determine the frequency of expression and prognostic value in two independent
populations. A control tissue microarray (TMA) was constructed using PD-L1-transfected …