[PDF][PDF] Can the suppressive activity of myeloid-derived suppressor cells be “chop” ped?

T Condamine, DI Gabrilovich - Immunity, 2014 - cell.com
T Condamine, DI Gabrilovich
Immunity, 2014cell.com
Can the Suppressive Activity of Myeloid-Derived Suppressor Cells Be “Chop‣ped?
Page 1 Immunity Previews Can the Suppressive Activity of Myeloid-Derived Suppressor
Cells Be ‘‘Chop’’ped? Thomas Condamine1 and Dmitry I. Gabrilovich1,* 1The Wistar
Institute, Philadelphia, PA 19104, USA *Correspondence: dgabrilovich@wistar.org http://dx.doi.org/10.1016/j.immuni.2014.08.016
Myeloid-derived suppressor cells (MDSCs) are one of the major negative regulators of
immune responses. In this issue of Immunity, Thevenot et al. (2014) showed that in tumors …
Myeloid-derived suppressor cells (MDSCs) are one of the major negative regulators of immune responses. In this issue of Immunity, Thevenot et al. (2014) showed that in tumors, the suppressive activity of MDSCs is regulated by transcription factor Chop.
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