A study of the extracellular matrix protein as the migration pathway of neural crest cells in the gut: analysis in human embryos with special reference to the …

T Fujimoto, J Hata, S Yokoyama, T Mitomi - Journal of pediatric surgery, 1989 - Elsevier
Immunocytochemical studies on the human embryo were made using antineuronal cell
antibody and a panel of anti-extracellular matrix protein antibodies such as fibronectin,
laminine, collagen type IV, and hyaluronic acid. All the enteric ganglia are shown to be from
a single, vagal neural crest source, although the recent dual gradient migration theory of
neural-crest-derived cells in the gut can be challenged. Neural-crest-derived cells first
appear in the mesenchyme of the developing esophagus at 4 weeks, and then migrate …