Development of a genomic metric that can be rapidly used to predict clinical outcome in severely injured trauma patients
AG Cuenca, LF Gentile, MC Lopez, R Ungaro… - Critical care …, 2013 - journals.lww.com
Objective: Many patients have complicated recoveries following severe trauma due to the
development of organ injury. Physiological and anatomical prognosticators have had limited
success in predicting clinical trajectories. We report on the development and retrospective
validation of a simple genomic composite score that can be rapidly used to predict clinical
outcomes. Design: Retrospective cohort study. Setting: Multi-institutional level 1 trauma
centers. Patients: Data were collected from 167 severely traumatized (injury severity score> …
development of organ injury. Physiological and anatomical prognosticators have had limited
success in predicting clinical trajectories. We report on the development and retrospective
validation of a simple genomic composite score that can be rapidly used to predict clinical
outcomes. Design: Retrospective cohort study. Setting: Multi-institutional level 1 trauma
centers. Patients: Data were collected from 167 severely traumatized (injury severity score> …