Allosteric effects of some antifibrinolytic amino acids on the catalytic activity of human plasmin
U Christensen - Biochimica et Biophysica Acta (BBA)-Enzymology, 1978 - Elsevier
The effects of l-lysine, 6-aminohexanoic acid, and trans-4-aminomethylcyclohexane-1-
carboxylic acid on the catalytic activity of plasmin (EC 3.4. 21.7) have been investigated. The
kinetics of the plasmin-catalysed hydrolysis of α-N-benzoyl-l-arginine ethyl ester in the
presence of these compounds have been studied at a number of different concentrations of
the three modifiers. They each exert two effects on the reaction, an activation and an
inhibition, the concentration dependencies of which are markedly different. They must …
carboxylic acid on the catalytic activity of plasmin (EC 3.4. 21.7) have been investigated. The
kinetics of the plasmin-catalysed hydrolysis of α-N-benzoyl-l-arginine ethyl ester in the
presence of these compounds have been studied at a number of different concentrations of
the three modifiers. They each exert two effects on the reaction, an activation and an
inhibition, the concentration dependencies of which are markedly different. They must …