Edetate sodium aerosol in Pseudomonas lung infection in cystic fibrosis

J Brown, CM Mellis, RE Wood - American Journal of Diseases of …, 1985 - jamanetwork.com
• In vitro and animal experimental data suggest the combination of edetate sodium (EDTA)
by aerosol plus oral antimicrobials might be effective in the treatment of
chronicPseudomonasinfection in patients with cystic fibrosis (CF). For six months we studied
the effects of edetate sodium administered by ultrasonic nebulizer to ten children with CF
and chronicPseudomonas aeruginosainfection in a double-blind, placebo-controlled,
crossover study. The children had evidence of mild to moderate disease at entry in the study …