Low vitamin D and high fibroblast growth factor 23 serum levels associate with infectious and cardiac deaths in the HEMO study

M Chonchol, T Greene, Y Zhang… - Journal of the …, 2016 - journals.lww.com
Longitudinal studies testing the relationship between repeated measures of vitamin D or
fibroblast growth factor 23 (FGF23) and infectious and cardiac hospitalizations and death in
hemodialysis patients have not been reported. We examined the association between yearly
25-hydroxyvitamin D (25 (OH) D), 1, 25-dihydroxyvitamin D (1, 25 (OH) 2 D), and FGF23
serum levels and various clinical outcomes using time-dependent Cox regression models
with repeated yearly measures and fixed-covariate Cox models with only baseline values …