Hemodynamic effects of staged hematocrit reduction in patients with stable cor pulmonale and severely elevated hematocrit levels

AB Weisse, CB Moschos, MJ Frank… - The American journal of …, 1975 - Elsevier
Patients with cor pulmonale and high hematocrit levels are often subjected to phlebotomy in
the belief that the adverse effects of high viscosity may outweigh the benefit of increased
oxygen carrying capacity. To evaluate this, 12 patients with stable cor pulmonale and
hematocrit values greater than 55 per cent were studied before and after a series of
venesections. Right heart and aortic pressures, cardiac output and blood gases were
measured at three mean hematocrit levels, 61 per cent (stage I), 50 per cent (stage II) and 44 …