Pulmonary vascular response to air-breathing exercise in humans following an 8-h exposure to hypoxia
M Herigstad, PA Robbins - Respiratory physiology & neurobiology, 2009 - Elsevier
This study is concerned with the pulmonary vasculature in euoxia after preconditioning with
8h of hypoxia. The particular question we ask is whether the pulmonary vasculature will
dilate normally with exercise or retain some degree of vasoconstriction, as has previously
been reported in studies involving longer exposures to the hypoxia of high altitude. Ten
subjects were studied on two separate days. On one day, subjects were exposed to 8h of
isocapnic hypoxia (end-tidal [Formula: see text] 55Torr) and on the other day to 8h of euoxia …
8h of hypoxia. The particular question we ask is whether the pulmonary vasculature will
dilate normally with exercise or retain some degree of vasoconstriction, as has previously
been reported in studies involving longer exposures to the hypoxia of high altitude. Ten
subjects were studied on two separate days. On one day, subjects were exposed to 8h of
isocapnic hypoxia (end-tidal [Formula: see text] 55Torr) and on the other day to 8h of euoxia …