Overview of Cytochrome P450 1B1 gene mutations in patients with primary congenital glaucoma
N Li, Y Zhou, L Du, M Wei, X Chen - Experimental eye research, 2011 - Elsevier
The objective of this study was to investigate the distribution of mutations in the Cytochrome
P450 1B1 gene (CYP1B1) in patients with primary congenital glaucoma (PCG) among
different populations. All identifiable original studies on CYP1B1 gene mutations of patients
with PCG were reviewed. Finally, DNA mutations within the CYP1B1 gene were identified in
542 patients with PCG according to 52 scientific articles and 147 distinct mutations were
found. The 3987G> A (G61E) missense mutation is a founder mutation in Middle Eastern …
P450 1B1 gene (CYP1B1) in patients with primary congenital glaucoma (PCG) among
different populations. All identifiable original studies on CYP1B1 gene mutations of patients
with PCG were reviewed. Finally, DNA mutations within the CYP1B1 gene were identified in
542 patients with PCG according to 52 scientific articles and 147 distinct mutations were
found. The 3987G> A (G61E) missense mutation is a founder mutation in Middle Eastern …