[HTML][HTML] Clinical implications of basic science discoveries: immune homeostasis and the microbiome—dietary and therapeutic modulation and implications for …

JA Fishman, AW Thomson - American Journal of Transplantation, 2015 - Elsevier
Links between the human microbiome and the innate and adaptive immune systems and
their impact on autoimmune and inflammatory diseases are only beginning to be
recognized. Characterization of the complex human microbial community is facilitated by
culture-independent nucleic acid sequencing tools and bioinformatics systems. Specific
organisms and microbial antigens are linked with initiation of innate immune responses that,
depending on the context, may be associated with tolerogenic or effector immune …