Placental changes in a first trimester missed abortion in maternal systemic lupus erythematosus with antiphospholipid syndrome: a case report and review of the …

R Nayar, JM Lage - Human pathology, 1996 - Elsevier
The placental lesions generally attributed to the effects of systemic lupus erythematosus
(SLE) on the decidua and placental villi include decidual vasculopathy, placental infarcts
and possibly intra-uterine growth retardation. The maternal decidual vessels in SLE show a
lesion termed “acute atherosis” which is histologically similar to acute vascular rejection in a
transplanted kidney. These changes can be so extensive as to result in complete vascular
occlusion, decreased placental perfusion and resultant placental villous infarction. In …