Genetic diversity of the Kaposi's sarcoma herpesvirus K1 protein in AIDS-KS in Zimbabwe

T White, M Hagen, I Gudza, IE White, B Ndemera… - Journal of Clinical …, 2008 - Elsevier
BACKGROUND: Kaposi's sarcoma-associated herpesvirus (KSHV) encodes genetically
diverse K1 alleles which have unique geographic distributions. Little is known about K1
genetic diversity in Zimbabwe where acquired immunodeficiency syndrome-associated KS
(AIDS-KS) is epidemic. OBJECTIVE: Evaluate K1 diversity in Zimbabwe and compare
Zimbabwean K1 diversity to other areas in Africa. STUDY DESIGN: K1 nucleotide sequence
was determined for AIDS-KS cases in Zimbabwe. K1 references sequences were obtained …