Normal and pathologic concentrations of uremic toxins

F Duranton, G Cohen, R De Smet… - Journal of the …, 2012 - journals.lww.com
An updated review of the existing knowledge regarding uremic toxins facilitates the design
of experimental studies. We performed a literature search and found 621 articles about
uremic toxicity published after a 2003 review of this topic. Eighty-seven records provided
serum or blood measurements of one or more solutes in patients with CKD. These records
described 32 previously known uremic toxins and 56 newly reported solutes. The articles
most frequently reported concentrations of β2-microglobulin, indoxyl sulfate, homocysteine …