[HTML][HTML] The chicken ovalbumin upstream promoter-transcription factors modulate genes and pathways involved in skeletal muscle cell metabolism
SA Myers, SCM Wang, GEO Muscat - Journal of Biological Chemistry, 2006 - ASBMB
The chicken ovalbumin upstream promoter-transcription factors (COUP-TFs) are" orphan"
members of the nuclear hormone receptor (NR) superfamily. COUP-TFs are involved in
organogenesis and neurogenesis. However, their role in skeletal muscle (and other major
mass tissues) and metabolism remains obscure. Skeletal muscle accounts for∼ 40% of total
body mass and energy expenditure. Moreover, this peripheral tissue is a primary site of
glucose and fatty acid utilization. We utilize small interfering RNA (siRNA)-mediated …
members of the nuclear hormone receptor (NR) superfamily. COUP-TFs are involved in
organogenesis and neurogenesis. However, their role in skeletal muscle (and other major
mass tissues) and metabolism remains obscure. Skeletal muscle accounts for∼ 40% of total
body mass and energy expenditure. Moreover, this peripheral tissue is a primary site of
glucose and fatty acid utilization. We utilize small interfering RNA (siRNA)-mediated …