We have identified in malignant melanoma an angiotumoral complex in which tumor cells
occupy a pericytic location along the endothelium of microvessels without evidence of
intravasation. We have suggested that this pericytic-like angiotropism could be a marker of
an extravascular migration of tumor cells along the abluminal surface of vessels. The
extravascular migratory metastasis proposed for melanoma has close analogies with glioma
migration. To compare our hypothesis of extravascular migration by melanoma with the …