[HTML][HTML] Endothelial cells express a novel, tumor necrosis factor-α-regulated variant of HOXA9
CV Patel, R Sharangpani, S Bandyopadhyay… - Journal of Biological …, 1999 - ASBMB
The expression of the class 1 homeobox (HOX) family of" master control" transcription
factors has been studied principally in embryogenesis and neoplasia in which HOX genes
play a critical role in cell proliferation, migration, and differentiation. We wished to test
whether HOX family members were also involved in a differentiation-like process occurring
in normal, diploid adult cells, that is, cytokine-induced activation of endothelial cells (EC).
Screening of a human EC cDNA library yielded several members of the A and B groups of …
factors has been studied principally in embryogenesis and neoplasia in which HOX genes
play a critical role in cell proliferation, migration, and differentiation. We wished to test
whether HOX family members were also involved in a differentiation-like process occurring
in normal, diploid adult cells, that is, cytokine-induced activation of endothelial cells (EC).
Screening of a human EC cDNA library yielded several members of the A and B groups of …