The expanding snoRNA world
JP Bachellerie, J Cavaillé, A Hüttenhofer - Biochimie, 2002 - Elsevier
In eukaryotes, the site-specific formation of the two prevalent types of rRNA modified
nucleotides, 2′-O-methylated nucleotides and pseudouridines, is directed by two large
families of snoRNAs. These are termed box C/D and H/ACA snoRNAs, respectively, and
exert their function through the formation of a canonical guide RNA duplex at the
modification site. In each family, one snoRNA acts as a guide for one, or at most two
modifications, through a single, or a pair of appropriate antisense elements. The two guide …
nucleotides, 2′-O-methylated nucleotides and pseudouridines, is directed by two large
families of snoRNAs. These are termed box C/D and H/ACA snoRNAs, respectively, and
exert their function through the formation of a canonical guide RNA duplex at the
modification site. In each family, one snoRNA acts as a guide for one, or at most two
modifications, through a single, or a pair of appropriate antisense elements. The two guide …