Epstein-Barr virus: transformation, cytopathic changes, and viral antigens in squirrel monkey and marmoset leukocytes
G Miller, T Shope, H Lisco, D Stitt… - Proceedings of the …, 1972 - National Acad Sciences
G Miller, T Shope, H Lisco, D Stitt, M Lipman
Proceedings of the National Academy of Sciences, 1972•National Acad SciencesBlood leukocytes of two species of new world primates, other than human, transform
following exposure to Epstein-Barr virus. The transformed simian cells produce Epstein-Barr
virus antigens and infectious (transforming) virus. The simian lymphoblastoid cells form
multinucleate giant cells that appear to be selective sites for the production of Epstein-Barr
virus. Multinucleate cells reveal intranuclear inclusions; in both species, a large proportion of
giant cells contain Epstein-Barr virus antigen detectable by immunofluorescence.
following exposure to Epstein-Barr virus. The transformed simian cells produce Epstein-Barr
virus antigens and infectious (transforming) virus. The simian lymphoblastoid cells form
multinucleate giant cells that appear to be selective sites for the production of Epstein-Barr
virus. Multinucleate cells reveal intranuclear inclusions; in both species, a large proportion of
giant cells contain Epstein-Barr virus antigen detectable by immunofluorescence.
Blood leukocytes of two species of new world primates, other than human, transform following exposure to Epstein-Barr virus. The transformed simian cells produce Epstein-Barr virus antigens and infectious (transforming) virus. The simian lymphoblastoid cells form multinucleate giant cells that appear to be selective sites for the production of Epstein-Barr virus. Multinucleate cells reveal intranuclear inclusions; in both species, a large proportion of giant cells contain Epstein-Barr virus antigen detectable by immunofluorescence.
National Acad Sciences