Presence of both odor identification and detection deficits in Alzheimer's disease
RL Doty, PF Reyes, T Gregor - Brain research bulletin, 1987 - Elsevier
Recent studies of Alzheimer's disease patients have demonstrated (a) marked structural and
biochemical alterations in brain regions associated with olfactory function (including the
olfactory bulb and entorhinal cortex) and (b) decrements in the ability to identify odorants. In
light of such findings, we administered the University of Pennsylvania Smell Identification
Test (UPSIT) and a forced-choice phenyl ethyl alcohol odor detection threshold test to a
relatively large number of patients diagnosed, on the basis of stringent criteria, as having …
biochemical alterations in brain regions associated with olfactory function (including the
olfactory bulb and entorhinal cortex) and (b) decrements in the ability to identify odorants. In
light of such findings, we administered the University of Pennsylvania Smell Identification
Test (UPSIT) and a forced-choice phenyl ethyl alcohol odor detection threshold test to a
relatively large number of patients diagnosed, on the basis of stringent criteria, as having …