Changes in activated T cells in the blood correlate with disease activity in multiple sclerosis
SJ Khoury, CRG Guttmann, EJ Orav… - Archives of …, 2000 - jamanetwork.com
Objective To determine whether changes in activation markers on peripheral blood T cells
correlate with disease activity in patients with multiple sclerosis. Design In a prospective
longitudinal study during 1 year, we analyzed the change in percentage of activated T
lymphocytes in the peripheral blood of 40 patients with multiple sclerosis in relation to
clinical findings and changes on brain magnetic resonance imaging (MRI) scans. The
patients underwent repeated imaging of the brain (mean number of MRIs for each patient …
correlate with disease activity in patients with multiple sclerosis. Design In a prospective
longitudinal study during 1 year, we analyzed the change in percentage of activated T
lymphocytes in the peripheral blood of 40 patients with multiple sclerosis in relation to
clinical findings and changes on brain magnetic resonance imaging (MRI) scans. The
patients underwent repeated imaging of the brain (mean number of MRIs for each patient …