High-resolution echocardiographic assessment of infarct size and cardiac function in mice with myocardial infarction
LJ Yuan, T Wang, ML Kahn, VA Ferrari - Journal of the American Society of …, 2011 - Elsevier
BACKGROUND: The aim of this study was to develop a simple and reasonably precise
echocardiographic method for the assessment of infarct size (IS) and cardiac dysfunction in
mice after myocardial infarction. METHODS: In vivo experiments were performed in
C57BL/6J wild-type mice (n= 18) before and 48 hours after left anterior descending coronary
artery ligation. Endocardial length-based echocardiographic IS was validated with that by
three different histologic measurements. Left ventricular function was evaluated. RESULTS …
echocardiographic method for the assessment of infarct size (IS) and cardiac dysfunction in
mice after myocardial infarction. METHODS: In vivo experiments were performed in
C57BL/6J wild-type mice (n= 18) before and 48 hours after left anterior descending coronary
artery ligation. Endocardial length-based echocardiographic IS was validated with that by
three different histologic measurements. Left ventricular function was evaluated. RESULTS …