[HTML][HTML] Regulation of membrane fusion in synaptic excitation-secretion coupling: speed and accuracy matter
SM Wojcik, N Brose - Neuron, 2007 - cell.com
SM Wojcik, N Brose
Neuron, 2007•cell.comUnlike most other secretory processes, neurotransmitter release at chemical synapses is
extremely fast, tightly regulated, spatially restricted, and dynamically adjustable at the same
time. In this review, we focus on recent discoveries of molecular and cell biological
processes that determine how fusion competence of vesicles is achieved and controlled in
order to suit the specific requirements of synaptic transmitter release with respect to speed
and spatial selectivity.
extremely fast, tightly regulated, spatially restricted, and dynamically adjustable at the same
time. In this review, we focus on recent discoveries of molecular and cell biological
processes that determine how fusion competence of vesicles is achieved and controlled in
order to suit the specific requirements of synaptic transmitter release with respect to speed
and spatial selectivity.
Unlike most other secretory processes, neurotransmitter release at chemical synapses is extremely fast, tightly regulated, spatially restricted, and dynamically adjustable at the same time. In this review, we focus on recent discoveries of molecular and cell biological processes that determine how fusion competence of vesicles is achieved and controlled in order to suit the specific requirements of synaptic transmitter release with respect to speed and spatial selectivity.
cell.com