[HTML][HTML] Multiple domains define the expression and regulatory properties of Foxp1 forkhead transcriptional repressors
B Wang, D Lin, C Li, P Tucker - Journal of Biological Chemistry, 2003 - ASBMB
The Foxp subfamily of forkhead/HNF3 transcription factors has recently been recognized
because of its involvement in autoimmune disease, speech and language disorders, and
lung development. Domains unique to this subfamily include a divergent DNA-binding
winged helix, a leucine zipper, a zinc finger, and a polyglutamine tract. Little is known about
the properties of these proteins that are fundamental to their function as transcription factors
nor how the Foxp sequence motifs regulate their transcriptional regulatory properties. We …
because of its involvement in autoimmune disease, speech and language disorders, and
lung development. Domains unique to this subfamily include a divergent DNA-binding
winged helix, a leucine zipper, a zinc finger, and a polyglutamine tract. Little is known about
the properties of these proteins that are fundamental to their function as transcription factors
nor how the Foxp sequence motifs regulate their transcriptional regulatory properties. We …