Congenital mirror movements: phenotypes associated with DCC and RAD51 mutations
EA Franz, R Chiaroni-Clarke, S Woodrow… - Journal of the …, 2015 - Elsevier
Congenital mirror movements (CMM) is a disorder characterized by unintentional mirroring
in homologous motor systems of voluntary movements on the opposite side, usually
affecting the distal upper extremities. Genetic analyses have revealed involvement of three
genes (DCC, RAD51, and DNAL4). We sought to distinguish whether different phenotypes
of CMM exist, and if so, whether they might map to different causative genes. We studied 14
individuals across five families with dominantly-inherited CMM. We used accelerometer …
in homologous motor systems of voluntary movements on the opposite side, usually
affecting the distal upper extremities. Genetic analyses have revealed involvement of three
genes (DCC, RAD51, and DNAL4). We sought to distinguish whether different phenotypes
of CMM exist, and if so, whether they might map to different causative genes. We studied 14
individuals across five families with dominantly-inherited CMM. We used accelerometer …