Efficacy of azelaic acid on hepatic key enzymes of carbohydrate metabolism in high fat diet induced type 2 diabetic mice
S Muthulakshmi, R Saravanan - Biochimie, 2013 - Elsevier
Azelaic acid (AzA), a C9 linear α, ω-dicarboxylic acid, is found in whole grains namely
wheat, rye, barley, oat seeds and sorghum. The study was performed to investigate whether
AzA exerts beneficial effect on hepatic key enzymes of carbohydrate metabolism in high fat
diet (HFD) induced type 2 diabetic C57BL/6J mice. C57BL/6J mice were fed high fat diet for
10 weeks and subjected to intragastric administration of various doses (20 mg, 40 mg and
80 mg/kg BW) of AzA daily for the subsequent 5 weeks. Rosiglitazone (RSG) was used as …
wheat, rye, barley, oat seeds and sorghum. The study was performed to investigate whether
AzA exerts beneficial effect on hepatic key enzymes of carbohydrate metabolism in high fat
diet (HFD) induced type 2 diabetic C57BL/6J mice. C57BL/6J mice were fed high fat diet for
10 weeks and subjected to intragastric administration of various doses (20 mg, 40 mg and
80 mg/kg BW) of AzA daily for the subsequent 5 weeks. Rosiglitazone (RSG) was used as …