Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial

A Heijl, MC Leske, B Bengtsson, L Hyman… - Archives of …, 2002 - jamanetwork.com
Objective To provide the results of the Early Manifest Glaucoma Trial, which compared the
effect of immediately lowering the intraocular pressure (IOP), vs no treatment or later
treatment, on the progression of newly detected open-angle glaucoma. Design Randomized
clinical trial. Participants Two hundred fifty-five patients aged 50 to 80 years (median, 68
years) with early glaucoma, visual field defects (median mean deviation,− 4 dB), and a
median IOP of 20 mm Hg, mainly identified through a population screening. Patients with an …