Principles and practices for treatment of cutaneous wounds with cultured skin substitutes
ST Boyce, GD Warden - The American journal of surgery, 2002 - Elsevier
Background: Skin substitutes prepared from cultured skin cells and biopolymers may reduce
requirements for donor skin autograft, and have been shown to be effective in treatment of
excised burns, burn scars, and congenital skin lesions. Data Sources: Cultured skin
substitutes (CSS) generate skin phenotypes (epidermal barrier, basement membrane) in the
laboratory, and restore tissue function and systemic homeostasis. Healed skin is smooth,
soft and strong, but develops irregular degrees of pigmentation. Quantitative analysis …
requirements for donor skin autograft, and have been shown to be effective in treatment of
excised burns, burn scars, and congenital skin lesions. Data Sources: Cultured skin
substitutes (CSS) generate skin phenotypes (epidermal barrier, basement membrane) in the
laboratory, and restore tissue function and systemic homeostasis. Healed skin is smooth,
soft and strong, but develops irregular degrees of pigmentation. Quantitative analysis …