Comparative genomic hybridization was used to map copy number abnormalities in 48 short-
term cell cultures established from different stages and types of human melanoma. A variety
of random and non-random chromosomal alterations were detected, with gains within
chromosomes 20q, 7q, 7p, 20p, 6p and 17q and losses in 9p, 10q, 6q, 10p, 4q, and 11q
being the most common observations. In addition, several other chromosomal loci were over-
or under-represented in subgroups of melanomas. For example, sequences on 3q26 were …