Roles of PI3Ks in leukocyte chemotaxis and phagocytosis
L Stephens, C Ellson, P Hawkins - Current opinion in cell biology, 2002 - Elsevier
L Stephens, C Ellson, P Hawkins
Current opinion in cell biology, 2002•ElsevierThrough selective disruption of phosphoinositide 3-kinase (PI3K) activity and the use of
green fluorescent protein tagged derivatives of domains capable of specifically binding the
lipid products of PI3Ks in vivo, it has been shown that this family of signalling enzymes have
vital and distinct roles in chemotaxis, phagocytosis and phagosome maturation in
leukocytes.
green fluorescent protein tagged derivatives of domains capable of specifically binding the
lipid products of PI3Ks in vivo, it has been shown that this family of signalling enzymes have
vital and distinct roles in chemotaxis, phagocytosis and phagosome maturation in
leukocytes.
Through selective disruption of phosphoinositide 3-kinase (PI3K) activity and the use of green fluorescent protein tagged derivatives of domains capable of specifically binding the lipid products of PI3Ks in vivo, it has been shown that this family of signalling enzymes have vital and distinct roles in chemotaxis, phagocytosis and phagosome maturation in leukocytes.
Elsevier