NETs and traps delay wound healing in diabetes

RJR Flach, MP Czech - Trends in Endocrinology & Metabolism, 2015 - cell.com
RJR Flach, MP Czech
Trends in Endocrinology & Metabolism, 2015cell.com
Diabetes is associated with dire peripheral sequelae including foot ulcers and amputations.
A recent article by Wong et al. demystifies this connection by demonstrating that the
neutrophil defense mechanism of extruding decondensed chromatin, termed NETosis,
mediates delayed wound healing in diabetes and provides a therapeutic strategy for this
indication.
Diabetes is associated with dire peripheral sequelae including foot ulcers and amputations. A recent article by Wong et al. demystifies this connection by demonstrating that the neutrophil defense mechanism of extruding decondensed chromatin, termed NETosis, mediates delayed wound healing in diabetes and provides a therapeutic strategy for this indication.
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