[HTML][HTML] Association between individual and combined SNPs in genes related to innate immunity and incidence of CMV infection in seropositive kidney transplant …

M Fernández-Ruiz, I Corrales, M Arias… - American Journal of …, 2015 - Elsevier
In this study, we assessed the association between single-nucleotide polymorphisms
(SNPs) in seven candidate genes involved in orchestrating the immune response against
cytomegalovirus (CMV) and the 12-month incidence of CMV infection in 315 CMV-
seropositive kidney transplant (KT) recipients. Patients were managed either by antiviral
prophylaxis or preemptive therapy. CMV infection occurred in 140 patients (44.4%),
including 13 episodes of disease. After adjusting for various clinical covariates, patients …