Advances in human proteomics at high scale with the SOMAscan proteomics platform
L Gold, JJ Walker, SK Wilcox, S Williams - New biotechnology, 2012 - Elsevier
In 1997, while still working at NeXstar Pharmaceuticals, several of us made a proteomic bet.
We thought then, and continue to think, that proteomics offers a chance to identify disease-
specific biomarkers and improve healthcare. However, interrogating proteins turned out to
be a much harder problem than interrogating nucleic acids. Consequently, the 'omics'
revolution has been fueled largely by genomics. High-scale proteomics promises to
transform medicine with personalized diagnostics, prevention, and treatment. We have now …
We thought then, and continue to think, that proteomics offers a chance to identify disease-
specific biomarkers and improve healthcare. However, interrogating proteins turned out to
be a much harder problem than interrogating nucleic acids. Consequently, the 'omics'
revolution has been fueled largely by genomics. High-scale proteomics promises to
transform medicine with personalized diagnostics, prevention, and treatment. We have now …