[HTML][HTML] Molecular signatures of mouse TRPV1-lineage neurons revealed by RNA-Seq transcriptome analysis

SC Goswami, SK Mishra, D Maric, K Kaszas… - The journal of pain, 2014 - Elsevier
Disorders of pain neural systems are frequently chronic and, when recalcitrant to treatment,
can severely degrade the quality of life. The pain pathway begins with sensory neurons in
dorsal root or trigeminal ganglia, and the neuronal subpopulations that express the transient
receptor potential cation channel, subfamily V, member 1 (TRPV1) ion channel transduce
sensations of painful heat and inflammation and play a fundamental role in clinical pain
arising from cancer and arthritis. In the present study, we elucidate the complete …