Immunomodulatory therapy versus surgery for Rasmussen syndrome in early childhood

Y Takahashi, E Yamazaki, J Mine, Y Kubota, K Imai… - Brain and …, 2013 - Elsevier
We examined seizure, cognitive, and motor outcomes in patients with Rasmussen syndrome
or Rasmussen encephalitis (RS), after recent initiation of immunomodulatory therapies.
Among 53 patients with a diagnosis of RS referred from all over Japan, 49 patients (male 22,
female 27) with symptoms and findings characteristic of RS were evaluated. Regular
intravenous immunoglobulin (IVIg) therapy was administered at a dose of 100 mg/kg/day,
etc. Regular steroid pulse therapy was conducted with methylprednisolone at a dose of 30 …