[HTML][HTML] Histone demethylase KDM6B promotes epithelial-mesenchymal transition

S Ramadoss, X Chen, CY Wang - Journal of Biological Chemistry, 2012 - ASBMB
Epithelial-mesenchymal transition (EMT) is a critical event that occurs in embryonic
development, tissue repair control, organ fibrosis, and carcinoma invasion and metastasis.
Although significant progress has been made in understanding the molecular regulation of
EMT, little is known about how chromatin is modified in EMT. Chromatin modifications
through histone acetylation and methylation determine the precise control of gene
expression. Recently, histone demethylases were found to play important roles in gene …