Galanin and galanin-like peptide modulate vasopressin and oxytocin release in vitro: the role of galanin receptors
J Wodowska, J Ciosek - Neuropeptides, 2014 - Elsevier
Galanin (Gal) and galanin-like peptide (GALP) may be involved in the mechanisms of the
hypothalamo-neurohypophysial system. The aim of the present in vitro study was to
compare the influence of Gal and GALP on vasopressin (AVP) and oxytocin (OT) release
from isolated rat neurohypophysis (NH) or hypothalamo-neurohypophysial explants (Hth–
NH). The effect of Gal/GALP on AVP/OT secretion was also studied in the presence of
galantide, the non-selective galanin receptors antagonist. Gal at concentrations of 10− 10 M …
hypothalamo-neurohypophysial system. The aim of the present in vitro study was to
compare the influence of Gal and GALP on vasopressin (AVP) and oxytocin (OT) release
from isolated rat neurohypophysis (NH) or hypothalamo-neurohypophysial explants (Hth–
NH). The effect of Gal/GALP on AVP/OT secretion was also studied in the presence of
galantide, the non-selective galanin receptors antagonist. Gal at concentrations of 10− 10 M …