Nationwide cohort study of the leukotriene receptor antagonist montelukast and incident or recurrent cardiovascular disease
E Ingelsson, L Yin, M Bäck - Journal of Allergy and Clinical Immunology, 2012 - Elsevier
BACKGROUND: The leukotriene pathway has been associated with an increased
cardiovascular risk. However, the effects of the antileukotriene treatment used in asthmatic
patients on cardiovascular outcomes have remained largely unexplored. OBJECTIVE: We
sought to examine a potential protective role of the leukotriene receptor antagonist
montelukast on future risk of incident and recurrent myocardial infarction and ischemic
stroke. METHODS: A nationwide population-based cohort of approximately 7 million …
cardiovascular risk. However, the effects of the antileukotriene treatment used in asthmatic
patients on cardiovascular outcomes have remained largely unexplored. OBJECTIVE: We
sought to examine a potential protective role of the leukotriene receptor antagonist
montelukast on future risk of incident and recurrent myocardial infarction and ischemic
stroke. METHODS: A nationwide population-based cohort of approximately 7 million …